The Advanced Peak Shape Tools folder provides advanced tools to manipulate peak shapes and find regions in sequencing data that exhibit a distinct shape. These tools are used by the ChIP-Seq algorithm (see ChIP-Seq Analysis), but they can also be used interactively to refine the results of ChIP-Seq peak calling or to perform shape-based analyses of sequencing data.
These tools are available under:
Toolbox | Epigenomics Analysis () | Advanced Peak Shape Tools ()
The Learn Peak Shape Filter tool allows you to build a new peak shape filter from sequencing data and a set of positive and negative regions.
The Apply Peak Shape Filter tool allows you to apply a peak shape filter to sequencing data to discover regions (peaks), which match a given peak shape.
The Score Regions tool allows you to apply a peak shape filter to score genomic regions according how they match a given peak shape.