Convert RNA to DNA

CLC Genomics Workbench lets you convert an RNA sequence into DNA, substituting the U residues (Urasil) for T residues (Thymine):

        select an RNA sequence in the Navigation Area | Toolbox in the Menu Bar | Classical Sequence Analysis (Image gene_and_protein_analysis) | Nucleotide Analysis (Image nucleotideanalyses)| Convert RNA to DNA (Image translateRNAtoDNA)

   or  right-click a sequence in Navigation Area | Toolbox | Classical Sequence Analysis (Image gene_and_protein_analysis) | Nucleotide Analysis (Image nucleotideanalyses)| Convert RNA to DNA (Image translateRNAtoDNA)

This opens the dialog displayed in figure 15.2:

Image translateRNAtoDNAwizard
Figure 15.2: Translating RNA to DNA.

If a sequence was selected before choosing the Toolbox action, this sequence is now listed in the Selected Elements window of the dialog. Use the arrows to add or remove sequences or sequence lists from the selected elements.

Click Next if you wish to adjust how to handle the results. If not, click Finish.

This will open a new view in the View Area displaying the new DNA sequence. The new sequence is not saved automatically. To save the sequence, drag it into the Navigation Area or press Ctrl + S (Image command_key_web + S on Mac) to activate a save dialog.

Note! You can select multiple RNA sequences and sequence lists at a time. If the sequence list contains DNA sequences as well, they will not be converted.