Amino acid changes

This tool annotates variants with amino acid changes given a track with coding regions and a reference sequence (see figure 26.28).

Image refiner-aminoacid
Figure 26.28: The amino acid changes annotation tool.

The result is a new track where each variant has information about the effect on the amino acid sequence of the corresponding protein. The nomenclature used for reporting is taken from Furthermore, you can select whether to filter away synonymous variants so that only variants that change the protein product will be retained in the result track.