System requirements

To work with CLC Microbial Genomics Module 22.1 you will need to have CLC Genomics Workbench version 22 installed on your computer. With exception of the requirements below, the system requirements of CLC Microbial Genomics Module 22.1 are the same as the ones required for the CLC Genomics Workbench (

Special requirements for the MLST Scheme tools.

The system requirements for the MLST Scheme tools depend on the size of the MLST schemes (both the number of alleles and the number of sequence types). A laptop with 16GB of memory is normally sufficient for 7-gene schemes or cgMLST schemes based on a moderate number of isolates. Typing or constructing larger schemes may require more memory, and in general, we recommend at least 64GB of memory when working with cg/wgMLST schemes based on more than 100 isolates.

Special requirements for the Taxonomic Profiler.

The quality performance of the Taxonomic Profiler depends on the reference database used - the more complete a database, the better the quality. However, running the Taxonomic Profiler with a given database size will require at least the same amount of memory. For example, running with a 14 GB database requires at least 16 GB of RAM, and running with a 56 GB database requires a minimum of 64 GB RAM. When creating your reference database with the Download Custom Microbial Reference Database tool, you will get a warning about the memory requirements needed for running the Taxonomic Profiler with this database.

Special requirements for De Novo Assemble Metagenome.

It is recommended to have at least 16 GB RAM when running the De Novo Assemble Metagenome.

The PCoA 3D viewer requirements are the same as the 3D Molecule Viewer.

The Sunburst viewer makes use of JavaFX and may not work on older Linux kernels. An updated list of requirements for JavaFX can be found at