CLC Microbial Genomics Module 23.0.2 is for use with CLC Genomics Workbench version 23 or newer. The system requirements for CLC Genomics Workbench are provided at http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=System_requirements.html.
The system requirements for CLC Microbial Genomics Module are the same as those for CLC Genomics Workbench, except for the following:
- Tools using DIAMOND and ShortBRED require a CPU that supports the AVX2 or NEON instruction sets.
The system requirements for the MLST Scheme tools depend on the size of the MLST schemes (both the number of alleles and the number of sequence types). A laptop with 16GB of memory is normally sufficient for 7-gene schemes or cgMLST schemes based on a moderate number of isolates. Downloading and constructing or typing with larger schemes may require more memory, and in general we recommend at least 64GB of memory when working with cg/wgMLST schemes based on more than 100 isolates.
The memory requirements of Refrence based OTU clustering are dependent on the size of the reference database used; more and longer sequences require more run time and memory. Newer version of common choices (e.g. the full SILVA SSU database) are likely to be too large for a 16 GB machine. Instead we recommend using clustered databases (e.g. the SILVA SSU 99% database) and/or otherwise filtering and subsetting the database, to minimize its size.
The PCoA 3D viewer requirements are described in http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=System_requirements.html.
The Sunburst viewer makes use of JavaFX and may not work on older Linux kernels. An updated list of requirements for JavaFX can be found at http://www.oracle.com/technetwork/java/javafx/downloads/supportedconfigurations-1506746.html.