CLC Microbial Genomics Module 23.0.1 is for use with CLC Genomics Workbench version 23 or newer. The system requirements for CLC Genomics Workbench are provided at http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=System_requirements.html.
The system requirements for CLC Microbial Genomics Module are the same as those for CLC Genomics Workbench, except for the following:
- Tools using DIAMOND and ShortBRED require a CPU that supports the AVX2 or NEON instruction sets.
Special requirements for the MLST Scheme tools.
The system requirements for the MLST Scheme tools depend on the size of the MLST schemes (both the number of alleles and the number of sequence types). A laptop with 16GB of memory is normally sufficient for 7-gene schemes or cgMLST schemes based on a moderate number of isolates. Downloading and constructing or typing with larger schemes may require more memory, and in general we recommend at least 64GB of memory when working with cg/wgMLST schemes based on more than 100 isolates.
Special requirements for Taxonomic Profiling.The performance of the Taxonomic Profiling tool depends on the reference database used - the more complete a database, the better the taxonomic profiling. However, running Taxonomic Profiling with a given database size will require at least the same amount of memory. For example, a 14 GB database requires at least 16 GB of RAM, and a 56 GB database requires a minimum of 64 GB RAM. When creating your reference database with the Download Custom Microbial Reference Database tool, you will get a warning about the memory requirements needed for running the Taxonomic Profiling tool with this database.
Special requirements for De Novo Assemble Metagenome.It is recommended to have at least 16 GB RAM when running the De Novo Assemble Metagenome.
The PCoA 3D viewer requirements are described in http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=System_requirements.html.
The Sunburst viewer makes use of JavaFX and may not work on older Linux kernels. An updated list of requirements for JavaFX can be found at http://www.oracle.com/technetwork/java/javafx/downloads/supportedconfigurations-1506746.html.