Upload using the Ingenuity Knowledge Base
IPA recognizes gene ids for several species, see https://qiagen.my.salesforce-sites.com/KnowledgeBase/KnowledgeNavigatorPage?id=kA41i000000L6BTCA0&categoryName=IPA for a full list. Successive uploads to IPA are attempted, until the upload is successful:
- If the statistical comparison contains gene ids from a recognized database (Ensembl, Entrez, Hugo, or RefSeq), the ids are uploaded to IPA using the corresponding IPA identifier type. Otherwise, the 'Name' column is uploaded with IPA identifier types for Ensembl, Entrez, GenBank, miRBase (mature) and RefSeq.
- If the previous upload fails, it could be because the gene identifiers of the uploaded species are not supported by IPA. Gene names are often conserved across species, so uploads are attempted with gene names formatted according to the IPA human (upper case e.g. BRCA1) or mouse/rat (capitalized e.g. Brca1) gene names formats, using the corresponding IPA gene symbol identifier types. Uploads are performed in decreasing order of the number of unformatted gene names matching the human and mouse/rat formats.
Note that upload is successful even if just one gene has been successfully identified by IPA. All performed uploads and their error messages from IPA for failed uploads are written to the log.
If all upload attempts fail, the upload errors from IPA will be displayed. The errors might indicate that the species is not supported by IPA and the gene names did not match any of the human, mouse and rat genes.