The advantage of running the BLAST search on NCBI servers is that you have readily access to the popular, and often very large, BLAST databases without having to download them to your own computer. The advantages of running BLAST on your own computer include that you can use your own sequence collections as blast databases, and that running big batch BLAST jobs can be faster and more reliable when done locally.
- BLAST at NCBI
- BLAST a partial sequence against NCBI
- BLAST against local data
- BLAST a partial sequence against a local database