This tool will compute a a taxonomic profiling index from a reference database. Indexes are then used as input to the Taxonomic Profiling tool. The computation of index files for taxonomic profiling is memory and hard-disk intensive due to the large sizes of reference databases usually employed for this task. The algorithm requires roughly the number of bases in bytes of memory (as indicated by the Download Microbial Reference Database tool), i.e., approximatively the size of the uncompressed reference database; and twice this amount in hard disk space.
To run the tool, go to:
Databases () | Taxonomic Analysis | Create Taxonomic Profiling Index ()
In the first dialog, select one or several nucleotide databases, for example downloaded with the Download Microbial Reference Database tool (figure 18.9).
The output is an index file and a report as seen in figure 18.10. The report list the number of sequence and basepairs that were indexed.