Create Trees
For a given set of aligned sequences (see Create an alignment) it is possible to infer their evolutionary relationships. In CLC Drug Discovery Workbench this may be done using one of two distance based methods (see Bioinformatics explained).
For a given set of aligned sequences (see Create an alignment) it is possible to infer their evolutionary relationships. In CLC Drug Discovery Workbench this may be done using a distance based method to generate a phylogenetic tree:
- Create Tree (
) Is a tool that uses distance estimates computed from multiple alignments to create trees. The user can select whether to use Jukes-Cantor distance correction or Kimura distance correction (Kimura 80 for nucleotides/Kimura protein for proteins) in combination with either the neighbor joining or UPGMA method (see Distance-based methods).
Subsections