Setting ploidy and genetic code
Clicking Next offers options for setting ploidy and genetic code (see figure 34.12):
Figure 34.12: Ploidy and genetic code.
- Maximum expected alleles. This is the ploidy of your organism (or
actually "the maximum expected number of alleles"). If set to 1, only
homozygous alleles are reported even if another allele is present as well. For
cancer samples, which often have a lot of genome duplications, we recommend a
setting of 3. For polyploid organisms like plants, a setting of 4 should be used.
Genetic code. For the table report, the variant's effect on the protein level is calculated, and the translation table specified here is used. When reporting the variant as a track, this setting has no effect, since the amino acid consequences are calculated separately (see Add information about amino acid changes).