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Browse the manual

• Introduction
  • System requirements
  • Licensing
  • Latest improvements
• Installation
  • Quick installation guide
  • Installing and running the Server
    • Installing the Server software
  • Silent installation
  • Upgrading an existing installation
    • Upgrading major versions
  • Allowing access through your firewall
  • Downloading a license
    • Windows license download
    • Mac OS license download
    • Linux license download
  • Starting and stopping the server
    • Microsoft Windows
    • Mac OS X
    • Linux
  • Installing relevant plugins in the Workbench
• Configuring and administering the server
  • Logging into the administrative interface
  • Adding locations for saving data
    • Adding a file system location
    • Rebuilding the index
  • Accessing files on, and writing to, areas of the server filesystem
  • Changing the listening port
  • Changing the tmp directory
    • Job node setups
  • Setting the amount of memory available for the JVM
  • Limiting the number of cpus available for use
  • Other configurations
    • HTTP settings
    • Audit log settings
    • Deployment of server information to CLC Workbenches
  • Server plugins
  • Queue
• Managing users and groups
  • Logging in the first time and the root password
  • User authentication using the web interface
    • Managing users using the web interface
    • Managing groups using the web interface
  • User authentication using the Workbench
    • Managing users through the Workbench
    • Managing groups through the Workbench
    • Adding users to a group
  • User statistics
• Access privileges and permissions
  • Controlling access to data
    • Setting permissions on a folder
    • Recycle bin
    • Technical notes about permissions and security
  • Global permissions
  • Customized attributes on data locations
    • Configuring which fields should be available
    • Editing lists
    • Removing attributes
    • Changing the order of the attributes
  • Filling in values
    • What happens when the sequence is copied to another data location?
    • Searching
• Job Distribution
  • Model I: Master server with execution nodes
    • Master and job nodes explained
    • User credentials on a master-job node setup
    • Configuring your setup
    • Installing Server plug-ins
  • Model II: Master server submitting to grid nodes
    • Requirements for CLC Grid Integration
    • Technical overview
    • Setting up the grid integration
    • Licensing of grid workers
    • Configuring licenses as a consumable resource
    • Configure grid presets
    • Controlling the number of cores utilized
    • Other grid worker options
    • Testing a Grid Preset
    • Client-side: starting CLC jobs on the grid
    • Grid Integration Tips
    • Understanding memory settings
• External applications
  • External applications integration: Basic configuration
  • External applications integration: Post-processing
  • External applications integration: Stream handling
  • External applications integration: Environment
    • Environmental Variables
    • Working directory
    • Execute as master process
  • External applications integration: Parameter flow
  • External applications integration: Velvet
    • Installing Velvet
    • Running Velvet from the Workbench
    • Understanding the Velvet configuration
  • External applications integration: Bowtie
    • Installing Bowtie
    • Understanding the Bowtie configuration
    • Parameter overview
    • Setting path for temporary data
    • Tools for building index files
  • Troubleshooting
    • Checking the configuration
    • Check your third party application
    • Is your Import/Export directory configured?
    • Check your naming
• Workflows
  • Installing and configuring workflows
  • Executing workflows
  • Automatic update of workflow elements
• Appendix
  • Use of multi-core computers
  • Troubleshooting
    • Check set-up
    • Bug reporting
  • Database configurations
    • Getting and installing JDBC drivers
    • Configurations for MySQL
  • SSL and encryption
    • Enabling SSL on the server
    • Logging in using SSL from the Workbench
    • Logging in using SSL from the CLC Server Command Line Tools
  • DRMAA libraries
    • DRMAA for LSF
    • DRMAA for PBS Pro
    • DRMAA for OGE or SGE
  • Consumable Resources
  • Third party libraries
• Bibliography

System requirements

The system requirements of CLC Genomics Server are:

• Windows XP, Windows Vista, or Windows 7, Windows Server 2003 or Windows Server 2008
• Mac OS X 10.6 or later. However, Mac OS X 10.5.8 is supported on 64-bit Intel systems.
• Linux: Red Hat 5 or later. SUSE 10.2 or later.
• Intel or AMD CPU required

• Memory: The numbers below give minimum and recommended amounts for systems running mapping and analysis tasks. The requirements suggested are based on the genome size.
  • E. coli K12 ( 4.6 megabases)
    • Minimum: 2Gb RAM
    • Recommended: 4Gb RAM
  • C. elegans ( 100 megabases) and Arabidopsis thaliana ( 120 megabases)
    • Minimum: 4Gb RAM
    • Recommended: 8Gb RAM
  • Zebrafish ( 1.5 gigabases)
    • Minimum: 8Gb RAM
    • Recommended: 16Gb RAM
  • Human ( 3.2 gigabases) and Mouse ( 2.7 gigabases)
    • Minimum: 24Gb RAM
    • Recommended: 48Gb RAM

• Special requirements for de novo assembly. De novo assembly may need more memory than stated above - this depends both on the number of reads and the complexity and size of the genome. See http://www.clcbio.com/white-paper for examples of the memory usage of various data sets.
• A 64-bit computer and operating system is necessary if you wish to utilize more than 2GB RAM.

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