Space requirements
The total size of the complete reference data set you can download is approximately 12 GB3.1. It is in a zipped format, and the total size after the data is unzipped is substantially larger. The amount of time it will take to download this amount of data depends on your network connection. It can take several hours, or longer on slower connections. When unzipped the size of the full reference dataset is about 75 GB3.2.
For reference, in April, 2014, the size of each individual reference data file was approximately:
| Database | Size |
|---|---|
| 1000 Genomes | 10 GB |
| CDS | 49 MB |
| ClinVar | 41 MB |
| PhastConc | 5 GB |
| COSMIC | 372 MB |
| dbSNP | 44 GB |
| dbSNP Common | 12 GB |
| Genes | 3 MB |
| Gene Ontology | 33 MB |
| HapMap | 3 GB |
| mRNA | 62 MB |
| Sequence | 683 MB |