Add Reads to Contigs
It is possible to add reads to existing contigs if extra reads are available - e.g. after resequencing of problematic regions. This is useful in regions with extremely low coverage (figure 6.1). The advantage of adding reads to the existing read mappings rather than making a new read mapping of old and new reads together is that all modifications that potentially have been made in the old reads will be preserved.
Figure 6.1: Example showing a region with low coverage that will benefit from adding reads to contigs. Extra reads to this region can be genereted using the Design Primers tool.
Subsections