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Introduction
- The concept of Biomedical Genomics Analysis
- System requirements
- Contact information
Data import and export
Reference Data Management
- QIAGEN Sets
SARS-CoV-2 workflows
- Identify QIAseq SARS-CoV-2 Low Frequency and Shared Variants (Illumina)
- Identify Ion AmpliSeq SARS-CoV-2 Low Frequency and Shared Variants (Ion Torrent)
- SARS-CoV-2 workflow output
  - Summary outputs
  - Sample specific outputs
QIAseq Panel Analysis
- The Analyze QIAseq Panels guide
- How to create a custom panel analysis workflow
  - Import QIAGEN Primers
- Create a custom Trim adapter list (optional)
Targeted DNA
- The Identify QIAseq DNA Variants ready-to-use workflows
- Create QIAseq DNA CNV Control Mapping workflows
  - Output from the Create QIAseq DNA CNV Control Samples workflow
- The Identify TMB Status ready-to-use workflows
  - Output from the Identify TMB Status workflow
- The Detect QIAseq MSI Status ready-to-use workflow
  - Output of the Detect QIAseq MSI Status workflow
- Detect MSI Status with Baseline Creation ready-to-use workflow
- Targeted DNA tools detailed description
Targeted RNAscan
- The Detect QIAseq RNAscan Fusions ready-to-use workflow
  - Output from the Detect QIAseq RNAscan Fusions workflow
- The Perform QIAseq RNA Fusion XP Analysis ready-to-use workflow
  - Output from the Perform QIAseq RNA Fusion XP Analysis workflow
- Interpretation of fusion results
- Targeted RNAscan tools detailed description
Immune Repertoire
- Perform QIAseq Immune Repertoire Analysis ready-to-use workflow
  - Output from the Perform QIAseq Immune Repertoire Analysis workflow
- QIAseq Immune Repertoire Expert Tools
  - Immune Repertoire Analysis
  - Compare Immune Repertoires
Targeted Multimodal
- Perform QIAseq Multimodal Analysis (Illumina) ready-to-use workflow
  - Output from the Perform QIAseq Multimodal Analysis (Illumina)
- Perform QIAseq Multimodal Analysis with TMB and MSI (Illumina) ready-to-use workflow
  - Output from the Perform QIAseq Multimodal Analysis with TMB and MSI (Illumina)
- Running the workflows in batch using Metadata
Targeted RNA
- The Quantify QIAseq RNA Expression ready-to-use workflow
  - Output from the Quantify QIAseq RNA Expression workflow
- Targeted RNA tools detailed description
  - The Quantify QIAseq RNA tool
UPX 3'
- Demultiplex QIAseq UPX 3' reads
- The Quantify QIAseq UPX 3' ready-to-use workflow
  - Output from the Quantify QIAseq UPX 3' workflow
Exome
- Identify QIAseq Exome Germline Variants
  - Output from the Identify QIAseq Exome Germline Variants ready-to-use workflow
- Create QIAseq Exome CNV Control Mapping
  - Output from the Create QIAseq Exome CNV Control Mapping workflow
- Identify QIAseq Exome Causal Inherited Variants in Trio
  - Output from the Identify QIAseq Exome Causal Inherited Variants in Trio ready-to-use workflow
Targeted Methyl
- The Detect QIAseq Methylation ready-to-use workflow
  - Output from the Detect QIAseq Methylation workflow
- Targeted Methyl associated tools
  - Finding differentially methylated regions
  - Create Methylation Level Heat Map
QCI Interpret Integration
- Configuration of the Upload to QCI Interpret tool
- The Upload to QCI Interpret tool
QIAseq miRNA Analysis
- QIAseq miRNA Quantification
  - QIAseq miRNA Quantification outputs
  - Naming isomiRs
- QIAseq miRNA Differential Expression
- QIAseq miRNA Expert Tools
  - Create UMI Reads for miRNA
TruSight Oncology 500
- The Perform TSO500 DNA Analysis (Illumina) workflow
  - Output from the Perform TSO500 DNA Analysis
- The Perform TSO500 RNA Analysis (Illumina) workflow
  - Output from the Perform TSO500 RNA Analysis
QIAGEN GeneRead DNA Panel Analysis
- The QIAGEN GeneRead Panel Analysis workflow
  - Output from the QIAGEN GeneRead Panel Analysis
- Trim Primers and their Dimers from Mapping
Ready-to-use workflows descriptions and guidelines
- General Workflow
- Somatic Cancer
- Hereditary Disease
Getting started
- Import sequencing data
- Prepare Raw Data
Whole genome sequencing (WGS)
- General Workflows (WGS)
  - Annotate Variants (WGS)
  - Identify Known Variants in One Sample (WGS)
- Somatic Cancer (WGS)
- Hereditary Disease (WGS)
Whole exome sequencing (WES)
- General Workflows (WES)
- Somatic Cancer (WES)
- Hereditary Disease (WES)
Targeted amplicon sequencing (TAS)
- General Workflows (TAS)
  - Annotate Variants (TAS)
  - Identify Known Variants in One Sample (TAS)
- Somatic Cancer (TAS)
- Hereditary Disease (TAS)
Whole Transcriptome Sequencing (WTS)
- Annotate Variants (WTS)
- Compare Variants in DNA and RNA
- Identify Candidate Variants and Genes from Tumor Normal Pair
- Identify Variants and Add Expression Values
- Identify and Annotate Differentially Expressed Genes and Pathways
General tools
- CNV and LOH Detection
- Structural Variant Caller
  - Output from the Structural Variant Caller
- Target Region Coverage Analysis
  - Output from Target Region Coverage Analysis
Batching workflows
Legacy tools
- Detect Fusion Genes
- Refine Fusion Genes
Appendices
- Install and uninstall plugins
  - Installation of plugins
  - Uninstalling plugins
Bibliography

The concept of Biomedical Genomics Analysis

The Biomedical Genomics Analysis plugin has primarily been developed for use in cancer and disease research to analyze next generation sequencing (NGS) data. The Biomedical Genomics Analysis plugin provides a variety of specialized tools, reference data for human and model species and a comprehensive collection of ready-to-use workflows that cover all steps from the initial data processing and quality assurance through data analyses, annotation, and reporting.

The Biomedical Genomics Analysis plugin is constantly updated with new functionality, and currently ready-to use workflows are provided for the following applications:

SARS-CoV-2
QIAseq Panel Analysis
Whole Genome Sequencing
TSO Panel Analysis
Whole Exome Sequencing
Targeted Amplicon Sequencing
Whole Transcriptome Sequencing
Small RNA Sequencing

All the workflows included in the Biomedical Genomics Analysis plugin run are configured to use Reference Data Sets. These are described further in QIAGEN Sets.