Introduction
Advanced Peak Shape Tools Plugin provides advanced tools to manipulate peak shapes and find regions in sequencing data that exhibit a distinct shape.
These tools are used by the ChIP-Seq algorithm (see http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=ChIP_Seq_Analysis.html), but they can also be used interactively to refine the results of ChIP-Seq peak calling or to perform shape-based analyses of sequencing data.
These tools are available under:
Toolbox | Epigenomics Analysis (
) |
Advanced Peak Shape Tools (
)
The Learn Peak Shape Filter tool allows you to build a new peak shape filter from sequencing data and a set of positive and negative regions.
The Apply Peak Shape Filter tool allows you to apply a peak shape filter to sequencing data to discover regions (peaks), which match a given peak shape.
The Score Regions tool allows you to apply a peak shape filter to score genomic regions according how they match a given peak shape.