Introduction

Advanced Peak Shape Tools Plugin provides advanced tools to manipulate peak shapes and find regions in sequencing data that exhibit a distinct shape. These tools are used by the ChIP-Seq algorithm (see http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=ChIP_Seq_Analysis.html), but they can also be used interactively to refine the results of ChIP-Seq peak calling or to perform shape-based analyses of sequencing data.

These tools are available under:

        Toolbox | Epigenomics Analysis (Image epigenomics) | Advanced Peak Shape Tools (Image adv_epigenomics)

The Learn Peak Shape Filter tool allows you to build a new peak shape filter from sequencing data and a set of positive and negative regions.

The Apply Peak Shape Filter tool allows you to apply a peak shape filter to sequencing data to discover regions (peaks), which match a given peak shape.

The Score Regions tool allows you to apply a peak shape filter to score genomic regions according how they match a given peak shape.